WHO WE ARE

Over 30 years experience in Molecular Modelling with >280 publications. Prof. Andrea Brancale is one of the scientific inventors on the Bcl3 inhibitor programme. Current roles; Chair Medicinal Chemistry at University of Chemistry and Technology (Prague), Member Board Of Directors, International Society for Antiviral Research, Co-Founder and Director at Ceridwen Oncology Ltd, Scientific Director at Life Sciences Research Network Wales. Previous roles; Professor of Medicinal Chemistry at Cardiff University, Scientific Director of the Life Science Research Network Wales

Over 30 years experience in cancer and cell biology research with >70 publications in cancer biology. Prof. Richard Clarkson is one of the scientific inventors on the Bcl3 inhibitor programme. Current roles; Director of European Cancer Stem Cell Research Institute

Over 25 years academic career in cancer drug discovery with >230 publications focused on translational drug discovery. Prof. Andrew Westwell is one of the scientific inventors on the Bcl3 inhibitor programme. Current roles; Prof. of Medicinal Chemistry at Cardiff University School of Pharmacy & Pharmaceutical Sciences. Board member, Velindre University NHS Trust, home to the Velindre Cancer Centre. Previous roles; Dean of Research & Innovation, College of Biomedical and Life Sciences, CU.

Over 20 years practicing breast medical oncology. Active in industry sponsored & cooperative group clinical trials from early phase to phase 3 studies. Current roles; Medical Oncologist at Allina Health Cancer Institute. Consultant & speaker at Novartis, Daiichi Sankyo & AstraZeneca. Previous roles; Served on NSABP Foundation & NRG breast cancer committees, Director of breast medical oncology at Piper Breast Centers, Clinical director of breast medical oncology at Avera Health, Dr Krie was instrumental in establishing robust clinical trials program in addiction to cutting edge research in genomic guided treatment of breast cancer.

Over 22 years of global experience in the pharmaceutical industry, in senior research, development & strategy roles. Successfully led product development in a wide range of therapeutic areas, bringing innovative medicines to patients. Previous roles; VP of Clinical Development at Tiziana Life Sciences, Head of Clinical Development at Glenmark Pharmaceuticals with accountability for a portfolio of new chemical entities in oncology and immunology, leading clinical development teams for rheumatology, dermatology, respiratory and rare diseases at Regeneron Pharmaceuticals.

Over 30 years experience in medical oncology with >100 publications. Works in experimental cancer medicine and in lower GI cancer and conducts translational and clinical research, particularly related to developmental therapeutics and colorectal cancer. Has been Chief Investigator on many local, national and international cancer clinical trials in both early and late phase settings. Current role: Professor in Gastrointestinal Oncology at the School of Cancer Sciences in the University of Glasgow and Honorary Consultant in Medical Oncology at the Beatson West of Scotland Cancer Centre. Previous roles: Clinical Director of the N. Ireland Cancer Trials Network and Clinical lead, Belfast Experimental Cancer Medicine Centre. Prof. Set up the first early phase cancer clinical trials programme in Ireland.

Over 25 years experience in both Medicine and Science with >90 publications in scientific and clinical cancer research journals. Principal Investigator >35 Early Phase Trials Chief Investigator of 2 Investigator Led National Portfolio trials, FAKTION and FURVA. Current roles; Specialty Lead for Cancer in Wales, Early Phase Cancer Trials Lead, and Clinical Director of Research at Velindre Cancer Centre. Prof. Jones set up Wales's only Cancer Phase 1 Trials Unit & opened its 1st ever First in Human Trial, leading Global recruitment on it.

Over 25 years experience in clinical pharmacology with >650 publications, his research covers clinical, basic, & theoretical pharmacokinetics and pharmacodynamics of diverse drugs. Current roles; Fellow of several scientific societies Previous roles; Asst. Professor of Pharmacology at Boston University School of Medicine, Director of the Clinical Pharmacokinetics Laboratory & Asst. Professor at University of New York at Buffalo. Served on many editorial boards & NIH review panels. Awards; Oscar B Hunter Career Award in Therapeutics from ASCPT(2018), AAPS Distinguished Pharmaceutical Scientist Award (2020)